Structural Basis of PxxDY motif recognition in SH3 binding

We have used the water signal to locate the midpoint of the 1H axis, and then have given it a reference value where the temperature and the pH have been taken into account. In this case the value is 4.793 ppm.

For the 13C axis, we then calculated the position of the transmitter using the DSS indirect shift ratio and ended up with this value of 175.571 ppm, in the carbonyl carbon region of the protein 13C spectrum. The midpoint of the aliphatic 13C spectrum is at 118 or 128 ppms from this value, depending on the spectrum.

For the 15N axis, we calculated the midpoint of the 15N spectrum from the 1H midpoint using the indirect shift ratio of liquid ammonia, 0.101329118.

epidermal growth factor receptor pathway substrate 8 related protein 1 [Homo sapiens]

epidermal growth factor receptor kinase substrate 8-like protein 1 isoform b [Homo sapiens]

epidermal growth factor receptor kinase substrate 8-like protein 1 isoform a [Homo sapiens]

PREDICTED: epidermal growth factor receptor kinase substrate 8-like protein 1 isoform X6 [Pan paniscus]

PREDICTED: epidermal growth factor receptor kinase substrate 8-like protein 1 isoform X10 [Pan paniscus]

PREDICTED: epidermal growth factor receptor kinase substrate 8-like protein 1 isoform X1 [Pan troglodytes]

RecName: Full=Epidermal growth factor receptor kinase substrate 8-like protein 1; Short=EPS8-like protein 1; AltName: Full=Epid

Case, Darden, Cheatham, III, Simmerling, Wang, Duke, Luo, ... and Kollman