wwPDB validation report of PDB entry 7ZYF

PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)

A and B chain differ at the end regarding sugars, ZN molecule and Ligand positions
Leucyl-cystinyl aminopeptidase, pregnancy serum form

methyl (2S)-2-[[(2S)-2-[[(2S,3R)-3-azanyl-2-oxidanyl-4-(4-oxidanylphenoxy)butanoyl]amino]-4-methyl-pentanoyl]amino]-3-(1H-indol-3-yl)propanoate

Insulin regulated aminopeptidase (IRAP) in complex with a nanomolar alpha hydroxy beta amino acid based inhibitor.

(chain 'A' and (resid 158 through 186 or (resid 187 and (name N or name CA or name C or name O or name CB )) or resid 188 through 222 or (resid 227 through 230 and (name N or name CA or name C or name O or name CB )) or resid 231 through 271 or resid 273 through 280 or (resid 281 and (name N or name CA or name C or name O or name CB )) or resid 282 through 333 or (resid 334 and (name N or name CA or name C or name O or name CB )) or resid 335 through 336 or (resid 337 and (name N or name CA or name C or name O or name CB )) or resid 338 or (resid 339 through 340 and (name N or name CA or name C or name O or name CB )) or resid 342 through 366 or (resid 367 and (name N or name CA or name C or name O or name CB )) or resid 368 through 390 or resid 392 through 398 or (resid 399 and (name N or name CA or name C or name O or name CB )) or resid 400 through 498 or resid 500 through 534 or (resid 535 and (name N or name CA or name C or name O or name CB )) or resid 536 through 625 or (resid 626 and (name N or name CA or name C or name O or name CB )) or resid 627 through 636 or (resid 637 through 649 and (name N or name CA or name C or name O or name CB )) or resid 650 through 662 or (resid 663 and (name N or name CA or name C or name O or name CB )) or resid 664 through 742 or (resid 743 and (name N or name CA or name C or name O or name CB )) or resid 744 through 793 or resid 795 through 834 or resid 836 through 950 or (resid 951 and (name N or name CA or name C or name O or name CB )) or resid 952 through 1027 or resid 1033 through 1034 or resid 1044 through 1045 or resid 1048 through 1102))

(chain 'B' and (resid 158 or (resid 159 and (name N or name CA or name C or name O or name CB )) or resid 160 through 271 or resid 273 through 390 or resid 392 through 447 or (resid 448 and (name N or name CA or name C or name O or name CB )) or resid 449 through 498 or resid 500 through 503 or (resid 504 and (name N or name CA or name C or name O or name CB )) or resid 505 through 541 or (resid 542 and (name N or name CA or name C or name O or name CB )) or resid 543 through 597 or resid 600 through 638 or (resid 649 and (name N or name CA or name C or name O or name CB )) or resid 650 through 736 or (resid 737 and (name N or name CA or name C or name O or name CB )) or resid 738 through 793 or resid 795 through 817 or (resid 818 and (name N or name CA or name C or name O or name CB )) or resid 819 through 834 or resid 836 through 1015 or (resid 1016 and (name N or name CA or name C or name O or name CB )) or resid 1017 through 1037 or resid 1632 through 1633 or resid 1641 through 1642 or resid 1645 through 1646))

The analyses of the Patterson function reveals a significant off-origin peak that is 28.40 % of the origin peak, indicating pseudo-translational symmetry. The chance of finding a peak of this or larger height by random in a structure without pseudo-translational symmetry is equal to 1.8538e-03. The detected translational NCS is most likely also responsible for the elevated intensity ratio. See the relevant section of the logfile for more details.

structure factor analysis and validation
geometric validation package for ligand chemistry in protein x-ray structures
20191225.v01 (using entries in the PDB archive December 25th 2019)