wwPDB validation report of PDB entry 4ZVP

CASP-7,Apoptotic protease Mch-3,CMH-1,ICE-like apoptotic protease 3,ICE-LAP3

Caspase-7 Y230A/W232M/S234N bound to DEVD inhibitor

Caspase-7 Y230A/W232M/S234N bound to VEID inhibitor

Caspase-7 wild-type bound to tetrapeptide inhibitor Ac-VEID-cho

Caspase-7 Y230V/W232M/Q276C bound to VEID inhibitor

Caspase-7 Y230V/W232Y/S234V/Q276D bound to VEID inhibitor

Caspase-7 Y230V/W232Y/S234V/Q276D bound to DEVD inhibitor

wild-type caspase-7 bound to DEVD inhibitor

wild-type caspase-7 bound to LDESD inbibitor

Caspase-7 (E.C.3.4.22.60), Peptide ACE-ASP-GLU-VAL-ASA
Caspase-7 Variant 2 (V2) with reprogrammed substrate specificity due to Y230V/W232M/Q276C substitutions bound to DEVD inhibitor.

The largest off-origin peak in the Patterson function is 4.58% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)