wwPDB validation report of PDB entry 4ZSP

Aspartyl protease 2,Asp 2,Beta-site amyloid precursor protein cleaving enzyme 1,Beta-site APP cleaving enzyme 1,Memapsin-2,Membrane-associated aspartic protease 2

HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT

BACE crystal structure with bicyclic aminothiazine inhibitor

The analyses of the Patterson function reveals a significant off-origin peak that is 45.29 % of the origin peak, indicating pseudo-translational symmetry. The chance of finding a peak of this or larger height by random in a structure without pseudo-translational symmetry is equal to 1.3500e-04. The detected translational NCS is most likely also responsible for the elevated intensity ratio. See the relevant section of the logfile for more details.

20191225.v01 (using entries in the PDB archive December 25th 2019)
structure factor analysis and validation
geometric validation package for ligand chemistry in protein x-ray structures