wwPDB validation report of PDB entry 2YJC

MAJOR EXCRETED PROTEIN, MEP, CATHEPSIN L1 HEAVY CHAIN, CATHEPSIN L1 LIGHT CHAIN

CRYSTAL STRUCTURE OF A CYSTEINE PROTEASE PROFORM

CRYSTAL STRUCTURE OF MHC CLASS II ASSOCIATED P41 II FRAGMENT IN COMPLEX WITH CATHEPSIN L

DESIGN OF NON-COVALENT INHIBITORS OF HUMAN CATHEPSIN L .FROM THE 96-RESIDUE PROREGION TO OPTIMIZED TRIPEPTIDES

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. HYDROGENS GENERATED IN REFMAC, THOSE WITH ZERO OCCUPANCY REMOVED, U VALUES REFINED INDIVIDUALLY COVALENT NITRILE BINDING TO CYS25 SG HAS TARGET BOND LENGTHS C-S 1.75, C-N 1.3 AND PLANAR GEOMETRY

The largest off-origin peak in the Patterson function is 7.93% of the height of the origin peak. No significant pseudotranslation is detected.

20191225.v01 (using entries in the PDB archive December 25th 2019)

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures