wwPDB validation report of PDB entry 1YCP

CHYMOTRYPSINOGEN NUMBERING (RATHER THAN SEQUENTIAL) SYSTEM IS USED, BASED ON THE TOPOLOGICAL ALIGNMENT WITH THE STRUCTURE OF CHYMOTRYPSINOGEN (H.BRANDSTETTER ET AL., 1992, J.MOL.BIOL., V. 226, 1085).

THE CRYSTAL STRUCTURE OF FIBRINOGEN-AA PEPTIDE 1-23 (F8Y) BOUND TO BOVINE THROMBIN EXPLAINS WHY THE MUTATION OF PHE-8 TO TYROSINE STRONGLY INHIBITS NORMAL CLEAVAGE AT ARGININE-16

THERE ARE TWO INDEPENDENT COMPLEXES IN THE ASYMMETRIC
UNIT:

COMPLEX 1
EPSILON THROMBIN: CHAINS J, K, M
FIBRINOPEPTIDE: CHAIN F

COMPLEX 2
ALPHA THROMBIN: CHAINS L, H
FIBRINOPEPTIDE: CHAIN N

BINDING SITE FOR CHAIN F OF FIBRINOPEPTIDE A-ALPHA

BINDING SITE FOR CHAIN N OF FIBRINOPEPTIDE A-ALPHA

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)