wwPDB validation report of PDB entry 2VXU

CRYSTAL STRUCTURE OF HUMAN IL-18 COMPLEXED TO MURINE REFERENCE ANTIBODY 125-2H FAB

CRYSTAL STRUCTURE OF HUMAN IGG ABT-325 FAB FRAGMENT

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. MOLECULE A (CHAINS H AND L) AND A CRYSTALLOGRAPHIC SYMMETRY MATE OF MOLECULE B (CHAINS I AND M) ARE RELATED BY TRANSLATIONAL PSEUDO-SYMMETRY. MOLECULE A IS TRANSFORMED ONTO MOLECULE B_SYM BY ROTATION OF 4.4 DEGREES ABOUT AN AXIS WITH DIRECTION COSINES (-0.6574, 0.3326, 0. 6762) FOLLOWED BY TRANSLATION OF (0.7249, 46.9819, 53.2092) ANGSTROM UNITS.

Crystal structure of murine reference antibody 125-2H Fab fragment

The analyses of the Patterson function reveals a significant off-origin peak that is 28.63 % of the origin peak, indicating pseudo-translational symmetry. The chance of finding a peak of this or larger height by random in a structure without pseudo-translational symmetry is equal to 1.7828e-03. The detected translational NCS is most likely also responsible for the elevated intensity ratio. See the relevant section of the logfile for more details.

20191225.v01 (using entries in the PDB archive December 25th 2019)

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures