wwPDB validation report of PDB entry 2VO7

CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT

CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA

PKI, PKI-ALPHA, CAMP- DEPENDENT PROTEIN KINASE INHIBITOR, MUSCLE/BRAIN ISOFORM

CRYSTAL STRUCTURES OF PROTEIN KINASE B SELECTIVE INHIBITORSIN COMPLEX WITH PROTEIN KINASE A AND MUTANTS

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH (1-(9H-PURIN-6-YL)PIPERIDIN-4-YL) METHANAMINE

STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTICSUBUNIT IN COMPLEX WITH H7 PROTEIN KINASE INHIBITOR1-(5- ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE

CRYSTAL STRUCTURE OF PROTEIN KINASE A IN COMPLEX WITHAZEPANE DERIVATIVE 1

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH C-PHENYL-C-(4-(9H-PURIN-6-YL)-PHENYL )-METHYLAMINE

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 7-AZAINDOLE

THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE INCOMPLEX WITH RHO-KINASE INHIBITOR H-1152P

PKA COMPLEXED WITH (S)-2-(1H-INDOL-3-YL )-1-(5-ISOQUINOLIN-6-YL-PYRIDIN-3- YLOXYMETHYL-ETYLAMINE

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 4-(4-CHLOROBENZYL)-1-(7H-PYRROLO(2,3-D )PYRIMIDIN-4-YL)PIPERIDIN-4-YLAMINE

MODEL STRUCTURE OF THE CATALYTIC SUBUNIT- REGULATORY SUBUNITDIMERIC COMPLEX OF THE CAMP -DEPENDENT PROTEIN KINASE

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 4-(4-CHLORO-PHENYL)-4-(4-(1H-PYRAZOL-4 -YL)-PHENYL)-PIPERIDINE

STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH A-443654

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 2-(4-CHLORO-PHENYL)-2-PHENYL-ETHYLAMINE

PROTEIN KINASE A FIVEFOLD MUTANT MODEL OF RHO-KINASE WITH Y-27632

PKA STRUCTURES OF INDAZOLE-PYRIDINE SERIES OF AKT INHIBITORS

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 5-METHYL-4-PHENYL-1H-PYRAZOLE

STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH ISOQUINOLINE-5-SULFONIC ACID ( 2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL) AMIDE

PROTEIN KINASE A VARIANT COMPLEX WITH COMPLETELY ORDERED N-TERMINAL HELIX

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 2-(4-(5-METHYL-1H-PYRAZOL-4-YL)-PHENYL )-ETHYLAMINE

CRYSTAL STRUCTURE OF PROTEIN KINASE A IN COMPLEX WITHAZEPANE DERIVATIVE 5

STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH (4R,2S)-5'-(4-(4- CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL) ISOQUINOLINE

PKA THREEFOLD MUTANT MODEL OF RHO-KINASE WITH INHIBITOR H-1152P

CRYSTAL STRUCTURE OF THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE COMPLEXED WITH A PHOSPHORYLATEDSUBSTRATE PEPTIDE AND DETERGENT

PKA DOUBLE MUTANT MODEL OF PKB IN COMPLEX WITH MGATP

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH (1-(9H-PURIN-6-YL)PIPERIDIN-4-YL)AMINE

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH (S)-2-(4-CHLORO-PHENYL)-2-(4-1H- PYRAZOL-4-YL)-PHENYL)-ETHYLAMINE

CRYSTAL STRUCTURE OF PROTEIN KINASE A IN COMPLEX WITHAZEPANE DERIVATIVE 4

MODEL STRUCTURE OF THE CATALYTIC SUBUNIT- REGULATORY SUBUNITDIMERIC COMPLEX OF THE C- AMP-DEPENDENT PROTEIN KINASE

PKA THREE FOLD MUTANT MODEL OF RHO-KINASE WITH Y-27632

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH METHYL-(4-(9H-PURIN-6-YL)-BENZYL)-AMINE

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH C-(4-(4-CHLOROPHENYL)-1-(7H-PYRROLO(2, 3-D)PYRIMIDIN-4-YL)PIPERIDIN-4-YL) METHYLAMINE

PKA FIVE FOLD MUTANT MODEL OF RHO-KINASE WITH H1152P

CAMP-DEPENDENT PROTEIN KINASE PKA CATALYTIC SUBUNIT WITHPKI-5-24

DUAL BINDING MODE OF BISINDOLYLMALEIMIDE 2 TO PROTEINKINASE A (PKA)

PROTEIN KINASE A FIVEFOLD MUTANT MODEL OF RHO-KINASE

STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTICSUBUNIT IN COMPLEX WITH H89 PROTEIN KINASE INHIBITORN-[2-(4- BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE

PKA STRUCTURES OF AKT, INDAZOLE-PYRIDINE INHIBITORS

THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE INCOMPLEX WITH RHO-KINASE INHIBITOR FASUDIL (HA-1077)

CRYSTAL STRUCTURE OF PROTEIN KINASE A IN COMPLEX WITHAZEPANE DERIVATIVE 8

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 6-(4-(4-(4-CHLORO-PHENYL)-PIPERIDIN-4- YL)-PHENYL)-9H-PURINE

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH A-443654

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH C-(4-(4-CHLOROBENZYL)-1-(7H-PYRROLO(2, 3-D)PYRIMIDIN-4-YL)PIPERIDIN-4-YL) METHYLAMINE

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH (R)-2-(4-CHLORO-PHENYL)-2-(4-1H- PYRAZOL-4-YL)-PHENYL)-ETHYLAMINE

PKA FIVEFOLD MUTANT MODEL OF RHO-KINASE WITH INHIBITORFASUDIL (HA1077)

STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTICSUBUNIT IN COMPLEX WITH H8 PROTEIN KINASE INHIBITOR[N-(2-METHYLAMINO) ETHYL]-5-ISOQUINOLINESULFONAMIDE

CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT INCOMPLEX WITH STAUROSPORINE

STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4- CHLOROBENZYLOXY) ETHYLAMINO)ETHYL)AMIDE

THE CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE(PKA) IN COMPLEX WITH RHO- KINASE INHIBITOR Y-27632

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. BROKEN DENSITY FOR PHE 54 OF THE GLYCINE LOOP. SOME INDICATIONS OF ALTERNATIVE CONFORMATIONS WERE PRESENT FOR THIS REGION BUT WERE POORLY DEFINED. ONLY THE DOMINANT CONFORMATION HAS BEEN BUILT.

CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT (E.C.2.7.11.11), CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA
Structure of PKA complexed with 4-(4-Chlorobenzyl)-1-(7H-pyrrolo(2,3- d)pyrimidin-4-yl)piperidin-4-ylamine

The largest off-origin peak in the Patterson function is 5.29% of the height of the origin peak. No significant pseudotranslation is detected.

20191225.v01 (using entries in the PDB archive December 25th 2019)

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures