wwPDB validation report of PDB entry 4TQI

convex prefocussing mirror and a Kirkpatrick-Baez pair of focussing mirrors

Cryogenically cooled channel cut Si[111] crystal monochromator

(2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid

Transthyretin (TTR) with similar fluorenone based inhibitor in dual binding mode

Transthyretin (TTR) with the same fluorenone based inhibitor in forward binding mode

Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid in a dual binding mode

The analyses of the Patterson function reveals a significant off-origin peak that is 37.54 % of the origin peak, indicating pseudo-translational symmetry. The chance of finding a peak of this or larger height by random in a structure without pseudo-translational symmetry is equal to 4.2239e-04. The detected translational NCS is most likely also responsible for the elevated intensity ratio. See the relevant section of the logfile for more details.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)