wwPDB validation report of PDB entry 5TM4

Side scattering bent cube i-beam single crystal asymmetric cut 4.965 degs

ligand-binding domain, UNP residues 125-381

Nuclear receptor-interacting peptide, UNP residues 686-698

5-{4-[(1S,4S,6R)-6-[(3-chlorophenoxy)sulfonyl]-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl]phenoxy}pentanoic acid

ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1

NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2

Estrogen receptor, Nuclear receptor coactivator 2
Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the OBHS-ASC Analog, 5-(4-((1R,4S,6R)-6-((3-chlorophenoxy)sulfonyl)-3-(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-2-en-2-yl)phenoxy)pentanoic acid

The largest off-origin peak in the Patterson function is 5.68% of the height of the origin peak. No significant pseudotranslation is detected.

20191225.v01 (using entries in the PDB archive December 25th 2019)

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures