wwPDB validation report of PDB entry 6TG0

Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1

Epidermal growth factor receptor (E.C.2.7.10.1)
Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 21a

(chain A and (resid 700 through 708 or (resid 709 and (name N or name CA or name C or name O or name CB )) or resid 710 through 738 or (resid 739 and (name N or name CA or name C or name O or name CB )) or resid 740 through 748 or (resid 749 through 750 and (name N or name CA or name C or name O or name CB )) or resid 751 through 777 or resid 779 through 801 or resid 803 through 811 or resid 813 through 951 or resid 953 through 961 or (resid 962 and (name N or name CA or name C or name O or name CB )) or resid 963 through 970 or resid 972 through 975 or resid 977 through 981 or (resid 982 and (name N or name CA or name C or name O or name CB )) or resid 983 through 984))

(chain B and ((resid 700 through 702 and (name N or name CA or name C or name O or name CB )) or resid 703 through 722 or (resid 723 and (name N or name CA or name C or name O or name CB )) or resid 724 through 747 or (resid 748 through 750 and (name N or name CA or name C or name O or name CB )) or resid 751 or (resid 752 and (name N or name CA or name C or name O or name CB )) or resid 754 through 757 or (resid 758 and (name N or name CA or name C or name O or name CB )) or resid 759 through 777 or resid 779 through 801 or resid 803 through 811 or resid 813 through 857 or resid 876 through 921 or (resid 922 and (name N or name CA or name C or name O or name CB )) or resid 923 through 951 or resid 953 through 970 or resid 972 through 975 or resid 977 through 984))

binding site for Di-peptide N78 B 1105 and CYS B 797

The largest off-origin peak in the Patterson function is 4.95% of the height of the origin peak. No significant pseudotranslation is detected.

20191225.v01 (using entries in the PDB archive December 25th 2019)

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures