wwPDB validation report of PDB entry 5SJK

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

ligand can only bind in this pose if amide is tautomeric or if Gln726 has swapped carboxamide. Density is clear for ligand and distance to nearby Tyr is enlarged so other conformation of Gln726 is likely;

Crystal Structure of human phosphodiesterase 10 in complex with 5,8-dichloro-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one

The largest off-origin peak in the Patterson function is 2.98% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation
geometric validation package for ligand chemistry in protein x-ray structures
20191225.v01 (using entries in the PDB archive December 25th 2019)