wwPDB validation report of PDB entry 2ROP

the construct used in the experiment is 202 aa long and contains the soluble domains 3 and 4 of ATP7B named also Wilson protein, the inter-domain linker (31 aa), a 17 aa portion of the linker connecting domains 2-3, a 12 aa portion of the linker connecting domains 4-5, and no tags.
HMA 3 and HMA 4, third soluble domain and fourth soluble domain

Copper pump 2, Wilson disease-associated protein, WND/140 kDa

THE SEQUENCE IS OF VARIANT AND THE RESIDUE IS ALA REFERRED IN ATP7B_HUMAN.

The construct investigated consists of domains 3 and 4 of the soluble N-terminal tail of ATP7B and of a inter-domain linker of 31 aa being essentially in a random coil form. The two domains reorient in solution independently of one another and the coordinates of the linker have been omitted.

Case, Darden, Cheatham, III, Simmerling, Wang, Duke, Luo, ... and Kollm

Solution structure of domains 3 and 4 of human ATP7B

geometric validation package for ligand chemistry in protein x-ray structures
assessment of nmr assigned chemical shifts
geometric validation of nmr ensemble structure
20191225.v01 (using entries in the PDB archive December 25th 2019)
domain identification of nmr ensemble structure
classification of nmr ensemble structure
nmr chemical shift validation and reference correction
random coil index prediction from nmr chemical shifts