wwPDB validation report of PDB entry 6REQ

ALPHA CHAINS A AND C INCLUDE COENZYME B12, AND THE INHIBITOR 3-CARBOXYPROPYL- COENZYME A . B12 IS PRESENT LARGELY AS REDUCED COB(II)ALAMIN, OR B12R.

METHYLMALONYL-COA MUTASE, 3-CARBOXYPROPYL-COA INHIBITOR COMPLEX

THE ASYMMETRIC UNIT OF THE CRYSTAL CONTAINS TWO HETERODIMERIC MOLECULES, EACH WITH AN ALPHA CHAIN (CHAINS A AND C, CORRESPONDING TO GENE MUTB) AND A BETA CHAIN (CHAINS B AND D, CORRESPONDING TO GENE MUTA).

MOLECULE 1 CONSISTS OF CHAINS A (ALPHA), B (BETA), WITH GLYCEROL (RESIDUE 3001) AND WATERS (1-580).

MOLECULE 2 CONSISTS OF CHAINS C (ALPHA), D (BETA), WITH GLYCEROL (RESIDUE 3002) AND WATERS (581-1155).

CHAIN A INCLUDES COENZYME B12 (RESIDUE 1800) AND THE INHIBITOR 3-CARBOXYPROPYL-COA (RESIDUE 1801).

CHAIN C INCLUDES COENZYME B12 (RESIDUE 2800) AND THE INHIBITOR 3-CARBOXYPROPYL-COA (RESIDUE 2801).

The largest off-origin peak in the Patterson function is 2.65% of the height of the origin peak. No significant pseudotranslation is detected.
structure factor analysis and validation
geometric validation package for ligand chemistry in protein x-ray structures
20191225.v01 (using entries in the PDB archive December 25th 2019)