wwPDB validation report of PDB entry 7R3N

PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)

Residues [1-22] encode a secretion signal which is should have been co-translationally removed.

IL-12B,Cytotoxic lymphocyte maturation factor 40 kDa subunit,CLMF p40,IL-12 subunit p40

chain A and (resid 23:109 or resid 350:355)

chain B and (resid 23:109 or resid 350:355)

chain C and (resid 23:109 or resid 350:355)

chain D and (resid 23:109 or resid 350:355)

mouse Interleukin-12 subunit beta - p80 homodimer in space group P21 crystal form 3

The analyses of the Patterson function reveals a significant off-origin peak that is 45.29 % of the origin peak, indicating pseudo-translational symmetry. The chance of finding a peak of this or larger height by random in a structure without pseudo-translational symmetry is equal to 1.3505e-04. The detected translational NCS is most likely also responsible for the elevated intensity ratio. See the relevant section of the logfile for more details.

structure factor analysis and validation
geometric validation package for ligand chemistry in protein x-ray structures
20191225.v01 (using entries in the PDB archive December 25th 2019)