wwPDB validation report of PDB entry 1QOU

INTER-MOLECULAR DISULPHIDE BOND FORMED IN THE CRYSTAL, BETWEEN RESIDUES A145 AND B145.

AMINO ACID NUMBERING: FOR EASE OF COMPARISON, THE NUMBERING SCHEME ADOPTED FOR THIS ENTRY IS BASED ON A SEQUENCE ALIGNMENT OF 38 MEMBERS OF THE PEBP FAMILY. THE HUMAN HOMOLOGUE HAS BEEN TAKEN AS THE REFERENCE (SEE PDB ENTRY 1BD9). ALL AMINO ACID NUMBERING IN THIS ENTRY RELATES TO THE SEQUENCE POSITION IN HUMAN PEBP.

THE REFINED MODEL OF THE A-CHAIN CONTAINS THE FOLLOWING RESIDUES OF THE SEQUENCE LISTED REFINED MODEL OF THE B-CHAIN CONTAINS THE FOLLOWING RESIDUES B32B- B130, B143-B175.

CEN (Centroradialis) protein from Antirrhinum

IN THE CRYSTAL THE PROTEIN FORMS A HOMO-
DIMER THROUGHAN INTER-CHAIN DISULPHIDE BOND. THIS
OLIGOMERIC STATEIS NOT EXPECTED TO REPRESENT THE
FUNCTIONAL STATE.HOWEVER, A ROLE FOR THIS DIMERIC
ASSOCIATION IN PROTEINFUNCTION CANNOT BE RULED OUT
.

The analyses of the Patterson function reveals a significant off-origin peak that is 21.48 % of the origin peak, indicating pseudo-translational symmetry. The chance of finding a peak of this or larger height by random in a structure without pseudo-translational symmetry is equal to 6.9571e-03. The detected translational NCS is most likely also responsible for the elevated intensity ratio. See the relevant section of the logfile for more details.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)