wwPDB validation report of PDB entry 5Q09

Growth-inhibiting protein 17,cDNA FLJ75786,highly similar to Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1),mRNA

THE INHIBITOR PYRIDINE GROUPS ARE NOT WELL ORDERED AND HAVE WEAK ELECTRON DENSITY AND HIGH B-FACTORS. THE ELECTRON DENSITY OF THE TERMINAL UREA LOOKS NOT COPLANAR WITH THE PYRIDINE.
Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-[4-bromo-6-(carbamoylamino)pyridin-2-yl]-3-[5-(2-methoxyethyl)-4-methylthiophen-2-yl]sulfonylurea
(chain A and (resid 9 through 37 or resid 39 through 61 or resid 72 through 139 or resid 141 through 335))
(chain B and (resid 9 through 37 or resid 39 through 139 or resid 141 through 335))
(chain C and (resid 9 through 37 or resid 39 through 139 or resid 141 through 335))
(chain D and (resid 9 through 37 or resid 39 through 61 or resid 72 through 139 or resid 141 through 335))
(chain E and (resid 9 through 37 or resid 39 through 61 or resid 72 through 139 or resid 141 through 335))
(chain F and (resid 9 through 37 or resid 39 through 139 or resid 141 through 335))
(chain G and (resid 9 through 37 or resid 39 through 139 or resid 141 through 335))
(chain H and (resid 9 through 37 or resid 39 through 139 or resid 141 through 335))
The largest off-origin peak in the Patterson function is 3.16% of the height of the origin peak. No significant pseudotranslation is detected.
20191225.v01 (using entries in the PDB archive December 25th 2019)
structure factor analysis and validation
geometric validation package for ligand chemistry in protein x-ray structures