wwPDB validation report of PDB entry 2OF0

Beta-site APP cleaving enzyme 1, Beta-site amyloid precursor protein cleaving enzyme 1, Membrane-associated aspartic protease 2, Memapsin-2, Aspartyl protease 2, Asp 2, ASP2

Crystal structure of beta secretase complexed with 1-amino-isoquinoline

Crystal structure of beta secretase complexed with 2-aminoquinoline

Crystal structure of beta secretase complexed with 2,3-diaminopyridine

Crystal structure of beta secretase complexed with compound 4

Crystal structure of beta secretase complexed with compound 3

Crystal structure of beta secretase complexed with compound 6a

Crystal structure of beta secretase complexed with compound 6b

Crystal structure of beta secretase complexed with compound 7

Crystal structure of beta secretase complexed with compound 8b

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

X-ray crystal structure of beta secretase complexed with compound 5

The largest off-origin peak in the Patterson function is 3.17% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)