wwPDB validation report of PDB entry 4L2Y

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Phosphatidylinositol 3-kinase regulatory subunit alpha

PI3-kinase subunit alpha, PI3K-alpha, PI3Kalpha, PtdIns-3-kinase subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha, PtdIns-3-kinase subunit p110-alpha, p110alpha, Phosphoinositide-3-kinase catalytic alpha polypeptide, Serine/threonine protein kinase PIK3CA

PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha

Crystal Structure of p110alpha complexed with niSH2 of p85alpha

Crystal Structure of p110alpha complexed with niSH2 of p85alpha and PI-103

HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT U VALUES: RESIDUAL ONLY

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (E.C.2.7.1.153, 2.7.11.1), Phosphatidylinositol 3-kinase regulatory subunit alpha
Crystal Structure of p110alpha complexed with niSH2 of p85alpha and compound 9d

The largest off-origin peak in the Patterson function is 3.17% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation
geometric validation package for ligand chemistry in protein x-ray structures
20191225.v01 (using entries in the PDB archive December 25th 2019)