wwPDB validation report of PDB entry 3KFN

Side scattering I-beam bent single crystal, asymmetric cut 4.9650 deg.

benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate

HIV-1 PROTEASE NL4-3 IN COMPLEX WITH INHIBITOR, TL-3, WILD TYPE

HIV Protease (PR) dimer without inhibitor; acetate in exo site

HIV Protease (PR) with inhibitor TL-3 bound, and DMSOs in exo site

HIV Protease (PR) dimer with inhibitor TL-3 bound and fragment 1F1 in the outside/top of flap

HIV Protease (PR) dimer with inhibitor TL-3 bound and fragment 2F4 in the outside/top of flap

THE INHIBITOR IS A C2 SYMMETRIC HIV PROTEASE

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS; U VALUES: REFINED INDIVIDUALLY
HIV PR dimer generated from PDB entry 2AZ8

HIV Protease (PR) with inhibitor TL-3 and fragment hit 4D9 by soaking

The largest off-origin peak in the Patterson function is 7.41% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)