wwPDB validation report of PDB entry 7JXK

PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER

Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1

( CHAIN D AND ( RESID 700:1007 OR RESID 1101:1103 ) )

( CHAIN A AND ( RESID 700:1007 OR RESID 1101:1102 ) )

( CHAIN C AND ( RESID 701:1007 OR RESID 1101:1102 ) )

( CHAIN F AND ( RESID 700:1007 OR RESID 1101:1102 ) )

( CHAIN E AND ( RESID 700:1007 OR RESID 1101:1102 ) )

( CHAIN B AND ( RESID 700:1007 OR RESID 1101:1101 ) )

EGFR kinase (T790M/V948R) in complex with PF-06747775 and JBJ-04-125-02

(chain A and (resid 701 through 857 or resid 876 through 907 or resid 909 through 984 or resid 990 through 1007))

(chain B and (resid 701 through 907 or resid 909 through 984 or resid 990 through 1007))

(chain C and (resid 701 through 857 or resid 876 through 907 or resid 909 through 984 or resid 990 through 1007))

(chain D and (resid 701 through 857 or resid 876 through 907 or resid 909 through 984 or resid 990 through 1007))

(chain E and (resid 701 through 857 or resid 876 through 907 or resid 909 through 1007))

(chain F and (resid 701 through 857 or resid 876 through 907 or resid 909 through 984 or resid 990 through 1007))

The analyses of the Patterson function reveals a significant off-origin peak that is 27.78 % of the origin peak, indicating pseudo-translational symmetry. The chance of finding a peak of this or larger height by random in a structure without pseudo-translational symmetry is equal to 2.0690e-03. The detected translational NCS is most likely also responsible for the elevated intensity ratio. See the relevant section of the logfile for more details.

structure factor analysis and validation
geometric validation package for ligand chemistry in protein x-ray structures
20191225.v01 (using entries in the PDB archive December 25th 2019)