wwPDB validation report of PDB entry 2JKH

STUART FACTOR, STUART-PROWER FACTOR, COAGULATION FACTOR X

CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX

FACTOR XA IN COMPLEX WITH THE INHIBITOR 4 -[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2- METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN -2-YL]CARBONYL]PIPERAZINE

CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH 43

FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S) -(3'-AMIDINO-3- BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXEDWITH RPR209685

CRYSTAL STRUCTURE OF THE ANTITHROMBIN-S195A FACTOR XA-PENTASACCHARIDE COMPLEX

AMINOPYRROLIDINE-RELATED TRIAZOLE FACTOR XA INHIBITOR

HUMAN FACTOR XA COMPLEXED WITH 2-[3-(15N- AMINO-15N-IMINO-13C-METHYL)PHENOXY]-6-[3 -(15N-AMINO-13C-METHYL)PHENOXY]-3,5- DIFLUORO-4-METHYLPYRIDINE (ZK-806299), BINDING MODELFROM DOUBLE REDOR NMR AND MD SIMULATIONS.

CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 79.

CRYSTAL STRUCTURE OF BLOOD COAGULATION FACTOR XA IN COMPLEXWITH ECOTIN M84R

FACTOR XA IN COMPLEX WITH THE INHIBITOR 3 -(6-(2'-((DIMETHYLAMINO)METHYL)-4-BIPHENYLYL )-7-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7- TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-1- YL)BENZAMIDE

CRYSTAL STRUCTURE OF 3-CHLORO-N-[4-CHLORO -2-[[(5-CHLORO-2-PYRIDINYL)AMINO]CARBONYL ]-6-METHOXYPHENYL]-4-[[(4,5-DIHYDRO-2- OXAZOLYL)METHYLAMINO]METHYL]-2- THIOPHENECARBOXAMIDE COMPLEXED WITH HUMAN FACTOR XA

HUMAN COAGULATION FACTOR XA COMPLEXD WITH M55590

STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS:BIARYL PYRROLIDIN-2- ONES INCORPORATING BASIC HETEROCYCLIC MOTIFS

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXEDWITH RPR200095

SELECTIVE AND DUAL ACTION ORALLY ACTIVE INHIBITORS OF THROMBIN AND FACTOR XA

CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 41.

CRYSTAL STRUCTURE OF FACTOR XA COMPLEXED TO RAZAXABAN

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXEDWITH RPR132747

CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH 21

HUMAN COAGULATION FACTOR XA COMPLEXD WITH M55165

THEORETICAL MODEL OF THE TISSUE FACTOR/ FACTOR VIIA/FACTORXA COMPLEX

HUNMAN COAGULATION FACTOR XA COMPLEXD WITH M55159

HUNMAN COAGULATION FACTOR XA COMPLEXD WITH M55143

CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 45.

STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1-BINDING, SUB- MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR

HUNMAN COAGULATION FACTOR XA COMPLEXD WITH M55532

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR208707

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR208815

CRYSTAL STRUCTURE OF 3-CHLORO-N-[4-CHLORO -2-[[(4-CHLOROPHENYL)AMINO]CARBONYL]PHENYL]- 4-[(4-METHYL-1-PIPERAZINYL)METHYL]-2- THIOPHENECARBOXAMIDE COMPLEXED WITHHUMAN FACTOR XA

CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH 50

HUMAN COAGULATION FACTOR XA COMPLEXD WITH M55192

CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH COMPOUND 45

HUNMAN COAGULATION FACTOR XA COMPLEXD WITH M54471

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXED WITH RPR128515

STRUCTURE AND PROPERTY BASED DESIGN OF FACTOR XA INHIBITORS: PYRROLIDIN-2-ONES WITH BIARYL P4 MOTIFS

CRYSTAL STRUCTURE OF THE INHIBITOR ZK-807834 (CI-1031)COMPLEXED WITH FACTOR XA

CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 125.

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXEDWITH RPR208944

HUNMAN COAGULATION FACTOR XA COMPLEXD WITH M55124

CRYSTAL STRUCTURE OF FACTOR XA IN COMPLEX WITH 1

HUNMAN COAGULATION FACTOR XA COMPLEXD WITH M55125

FACTOR XA IN COMPLEX WITH (R)-2-(3- ADAMANTAN-1-YL-UREIDO)-3-(3-CARBAMIMIDOYL- PHENYL)-N-PHENETHYL-PROPIONAMIDE

HUNMAN COAGULATION FACTOR XA COMPLEXD WITH M55113

FACTOR XA IN COMPLEX WITH THE INHIBITOR 1 -[6-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO(5, 4-C)PYRIDIN-2-YL] CARBONYL-2-CARBAMOYL-4 -(6-CHLORONAPHTH-2-YLSULPHONYL)PIPERAZINE

FACTOR XA IN COMPLEX WITH THE INHIBITOR 1 -(3-AMINO-1,2-BENZISOXAZOL-5-YL)-6-(2 '-(((3R)-3-HYDROXY-1-PYRROLIDINYL)METHYL)-4 -BIPHENYLYL)-3-(TRIFLUOROMETHYL)-1,4,5,6- TETRAHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE

CRYSTAL STRUCTURE OF HUMAN COAGULATION FACTOR XA COMPLEXEDWITH FXV673

HUNMAN COAGULATION FACTOR XA COMPLEXD WITH M54476

ENGINEERED RESIDUE IN CHAIN A, ARG 372 TO GLU
ARG-GLU MUTANT. THE RESIDUE NUMBERING IN THE CATALYTIC DOMAIN FOLLOWS THAT OF CHYMOTRYPSINOGEN

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. HYDROGENS HAVE NOT BEEN ADDED

ACTIVATED FACTOR XA HEAVY CHAIN (E.C.3.4.21.6), FACTOR X LIGHT CHAIN (E.C.3.4.21.6)

The largest off-origin peak in the Patterson function is 8.70% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)