wwPDB validation report of PDB entry 6HUG

Human full-length heteromeric alpha1beta3gamma2L GABA(A)R in complex with picrotoxin and megabody Mb38.

Potential signal peptide:
MKKSPGLSDY LWAWTLFLST LTGRSYG
FLAG tag:
DYKDDDDK

Gamma-aminobutyric acid receptor subunit alpha-1

Gamma-aminobutyric acid receptor subunit beta-3

Linker sequence:
GGSGGSGGSGK
1D4 tag:
TETSQVAPA

Gamma-aminobutyric acid receptor subunit gamma-2

[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate

(1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione

CryoEM structure of human full-length alpha1beta3gamma2L GABA(A)R in complex with picrotoxin and megabody Mb38.

Calculated fsc threesigma indicator curve
geometric validation package for ligand chemistry in protein x-ray structures
20191225.v01 (using entries in the PDB archive December 25th 2019)