wwPDB validation report of PDB entry 5HID

Liquid nitrogen-cooled double crystal, non fixed exit slit. Si(111)

Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1

BRAF Kinase domain b3aC loop deletion mutant in complex with sorafenib

BRAF Kinase domain b3aC loop deletion mutant in complex with dabrafenib

Serine/threonine-protein kinase B-raf (E.C.2.7.11.1)
BRAF Kinase domain b3aC loop deletion mutant in complex with AZ628

The analyses of the Patterson function reveals a significant off-origin peak that is 55.81 % of the origin peak, indicating pseudo-translational symmetry. The chance of finding a peak of this or larger height by random in a structure without pseudo-translational symmetry is equal to 2.9954e-05. The detected translational NCS is most likely also responsible for the elevated intensity ratio. See the relevant section of the logfile for more details.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)