wwPDB validation report of PDB entry 4H6O

T.cruzi CYP51 in complex with antifungal drug posaconazole

HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT

Sterol 14-alpha demethylase (E.C.1.14.13.70)
Sterol 14-alpha demethylase (CYP51)from Trypanosoma cruzi in complex with the inhibitor NEU321 (1-(3-(4-chloro-3,5-dimethylphenoxy)benzyl)-1H-imidazole

The largest off-origin peak in the Patterson function is 4.96% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)