wwPDB validation report of PDB entry 6H41

PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)

extracellullar domain of the human interleukin-5 receptor subunit alpha (Uniprot: Q01344-2), cysteine 66 is replaced with alanine

monomeric cyclic IL-5 inhibiting peptide AF17121, disulfide-bridge between Cys4 and Cys15

3QT2 contains the IL-5 receptor subunit alpha bound to its native ligand IL-5

Interleukin-5 receptor subunit alpha, VAL-ASP-GLU-CYS-TRP-ARG-ILE-ILE-ALA-SER-HIS-THR-TRP-PHE-CYS-ALA-GLU-GLU
Structure of the complex of the IL-5 inhibitory peptide AF17121 bound to the IL-5 receptor IL-5Ralpha

The largest off-origin peak in the Patterson function is 3.06% of the height of the origin peak. No significant pseudotranslation is detected.

20191225.v01 (using entries in the PDB archive December 25th 2019)

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures