wwPDB validation report of PDB entry 2H42

cGMP-specific 3',5'-cyclic phosphodiesterase

CGB-PDE, cGMP-binding cGMP-specific phosphodiesterase

Crystal structure of PDE5 in complex with sildenafil

Crystal structure of the catalytic domain of unliganded PDE5

cGMP-specific 3',5'-cyclic phosphodiesterase (E.C.3.1.4.35)

Biological unit may be a monomer. However, the crystallographic asymmetric unit contains 3 molecules.

The largest off-origin peak in the Patterson function is 2.63% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)