wwPDB validation report of PDB entry 3FTV

Leukotriene A(4) hydrolase, LTA-4 hydrolase

Leukotriene A4 hydrolase in complex with inhibitor 4-[(2S)-2-{[4-(4-chlorophenoxy)phenoxy]methyl}pyrrolidin-1-yl]butanoate

Leukotriene A4 hydrolase in complex with resveratrol

Leukotriene A4 hydrolase in complex with dihydroresveratrol

Leukotriene A4 hydrolase in complex with fragments N-(pyridin-3-ylmethyl)aniline and acetate

Leukotriene A4 hydrolase in complex with dihydroresveratrol and bestatin

Leukotriene A4 hydrolase in complex with fragment 3-(benzyloxy)pyridin-2-amine

Leukotriene A4 hydrolase in complex with fragment 2-(pyridin-3-ylmethoxy)aniline

Leukotriene A4 hydrolase in complex with fragment 4-(4-fluorobenzoyl)pyridine

Leukotriene A4 hydrolase in complex with fragment 4-(2-amino-1,3-thiazol-4-yl)phenol

Leukotriene A4 hydrolase in complex with (5-thiophen-2-ylthiophen-2-yl)methylamine

Leukotriene A4 hydrolase in complex with fragment (4-thiophen-2-ylphenyl)methanamine

Leukotriene A4 hydrolase in complex with N-methyl-1-(2-thiophen-2-ylphenyl)methanamine

Leukotriene A4 hydrolase in complex with fragment 5-chloroindole and bestatin

Leukotriene A4 hydrolase in complex with fragment 5-fluoroindole and bestatin

Leukotriene A4 hydrolase in complex with fragment 5-hydroxyindole and bestatin

Leukotriene A4 hydrolase in complex with N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline

Leukotriene A4 hydrolase in complex with 5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole

Leukotriene A4 hydrolase in complex with 1-[2-(1H-indol-5-yloxy)ethyl]piperidine-4-carboxylic acid

Leukotriene A4 hydrolase in complex with pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanone

Leukotriene A4 hydrolase in complex with (R)-pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanol

Leukotriene A4 hydrolase in complex with {4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Leukotriene A4 hydrolase in complex with fragment N-(pyridin-3-ylmethyl)aniline

The largest off-origin peak in the Patterson function is 4.42% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)