wwPDB validation report of PDB entry 5FEE

Single crystal, cylindrically bent, Si(220)

Inhibitor is covalently linked to Cys797.

Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1

Wild-type version of EGFR kinase domain complexed with the same inhibitor.

Epidermal growth factor receptor (E.C.2.7.10.1)
EGFR kinase domain T790M mutant in complex with a covalent aminobenzimidazole inhibitor.

The largest off-origin peak in the Patterson function is 2.84% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)