wwPDB validation report of PDB entry 4FCP

Heat shock 86 kDa, HSP 86, HSP86, Renal carcinoma antigen NY-REN-38

HYDROGENS HAVE BEEN USED IF PRESENT IN THE INPUT

Targetting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo [2,3-d] pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization

The analyses of the Patterson function reveals a significant off-origin peak that is 39.46 % of the origin peak, indicating pseudo-translational symmetry. The chance of finding a peak of this or larger height by random in a structure without pseudo-translational symmetry is equal to 3.1633e-04. The detected translational NCS is most likely also responsible for the elevated intensity ratio. See the relevant section of the logfile for more details.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)