wwPDB validation report of PDB entry 3E8N

Dual specificity mitogen-activated protein kinase kinase 1

MAP kinase kinase 1, MAPKK 1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK1

Dual specificity mitogen-activated protein kinase kinase 1 (E.C.2.7.12.2)
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) complexed with a potent inhibitor RDEA119 and MgATP

MEK1 IS A MONOMER IN SOLUTION AND IN THE ASYMMETRIC UNIT

The largest off-origin peak in the Patterson function is 3.50% of the height of the origin peak. No significant pseudotranslation is detected.

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures

20191225.v01 (using entries in the PDB archive December 25th 2019)