wwPDB validation report of PDB entry 4CYF

PANTETHEINE HYDROLASE, TIFF66, VASCULAR NON-INFLAMMATORY MOLECULE 1, VANIN-1, HUMAN VANIN-1

THE STRUCTURE OF VANIN-1: DEFINING THE LINK BETWEEN METABOLIC DISEASE, OXIDATIVE STRESS AND INFLAMMATION

STAPHYLOCOCCUS AUREUS 7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN- PYROPHOSPHOKINASE IN COMPLEX WITH AMPCPP

FLAG TAG AT N-TERMINUS. PRO-PEPTIDE AT C-TERMINUS HAS BEEN REMOVED IN CONSTRUCT TO GIVE THE MATURE PROTEIN

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES REFINED INDIVIDUALLY. WE FIND GLYCOSYLATION AT ASN RESIDUES 38, 130, 315 AND 353 IN THIS CRYSTAL FORM. WE ALSO FIND GLYCOSYLATION AT POSITION 200 IN A DIFFERENT CRYSTAL FORM AND THIS IS CONFIRMED BY MASS SPEC ANALYSIS.

The largest off-origin peak in the Patterson function is 2.52% of the height of the origin peak. No significant pseudotranslation is detected.

20191225.v01 (using entries in the PDB archive December 25th 2019)

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures