wwPDB validation report of PDB entry 4CTY

CONSTITUTIVE NOS, CNOS, EC-NOS, ENDOTHELIAL NOS, ENOS, NOS TYPE III, NOSIII

STRUCTURE OF RAT NEURONAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH (S)-6-(2-AMINO-2-(3-(2-(6 -AMINO-4-METHYLPYRIDIN-2-YL)ETHYL)PHENYL)ETHYL)-4- METHYLPYRIDIN-2-AMINE

STRUCTURE OF RAT NEURONAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH (R)-6-(2-AMINO-2-(3-(2-(6 -AMINO-4-METHYLPYRIDIN-2-YL)ETHYL)PHENYL)ETHYL)-4- METHYLPYRIDIN-2-AMINE

STRUCTURE OF RAT NEURONAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH 2-(6-AMINO-4-METHYLPYRIDIN-2 -YL)-1-(3-(2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL )PHENYL)ETHAN-1-OL

STRUCTURE OF RAT NEURONAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH (S)-2-(6-(2,5-DIMETHYL-1H- PYRROL-1-YL)-4-METHYLPYRIDIN-2-YL)-1-(3-(2-(4- METHYLPYRIDIN-2-YL)ETHYL)PHENYL)ETHAN-1-AMINE

STRUCTURE OF RAT NEURONAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH 6-(3-AMINO-2-(3-(2-(6- AMINO-4-METHYLPYRIDIN-2-YL)ETHYL)PHENYL)PROPYL)-4- METHYLPYRIDIN-2-AMINE

STRUCTURE OF RAT NEURONAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH 6-(3-AMINO-2-(6-(2-(6- AMINO-4-METHYLPYRIDIN-2-YL)ETHYL)PYRIDIN-2-YL)PROPYL )-4-METHYLPYRIDIN-2-AMINE

STRUCTURE OF RAT NEURONAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH (R)-6-(3-AMINO-2-(5-(2-(6 -AMINO-4-METHYLPYRIDIN-2-YL)ETHYL)PYRIDIN-3-YL) PROPYL)-4-METHYLPYRIDIN-2-AMINE

STRUCTURE OF RAT NEURONAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH (S)-6-(3-AMINO-2-(5-(2-(6 -AMINO-4-METHYLPYRIDIN-2-YL)ETHYL)PYRIDIN-3-YL) PROPYL)-4-METHYLPYRIDIN-2-AMINE

STRUCTURE OF BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH (S)-2-(6-(2,5-DIMETHYL -1H-PYRROL-1-YL)-4-METHYLPYRIDIN-2-YL)-1-(3-(2-( 4-METHYLPYRIDIN-2-YL)ETHYL)PHENYL)ETHAN-1-AMINE

STRUCTURE OF BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH (R)-6-(3-AMINO-2-(5-( 2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL)PYRIDIN-3-YL )PROPYL)-4-METHYLPYRIDIN-2-AMINE

STRUCTURE OF BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN IN COMPLEX WITH (S)-6-(3-AMINO-2-(5-( 2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL)PYRIDIN-3-YL )PROPYL)-4-METHYLPYRIDIN-2-AMINE

CACODYLIC ACID (CAS): DIMETHYL ARSENIC MOIETY DERIVED FROM CACODYLATE BUFFER
RESIDUE 100 IS FOUND AS AN ARG IN STRUCTURE BUT IS A CYS IN DATABASE

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES WITH TLS ADDED. RESIDUES 110 TO 120 IN BOTH CHAIN A AND CHAIN B ARE DISORDERED.

NITRIC OXIDE SYNTHASE, ENDOTHELIAL (E.C.1.14.13.39)
Structure of bovine endothelial nitric oxide synthase heme domain in complex with (R)-6-(2-Amino-2-(3-(2-(6-amino-4-methylpyridin-2-yl) ethyl)phenyl)ethyl)-4-methylpyridin-2-amine

The largest off-origin peak in the Patterson function is 3.47% of the height of the origin peak. No significant pseudotranslation is detected.

20191225.v01 (using entries in the PDB archive December 25th 2019)

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures