wwPDB validation report of PDB entry 4CD0

TYROSINE KINASE DOMAIN, RESIDUES 1093-1411

STRUCTURE OF THE HUMAN ANAPLASTIC LYMPHOMA KINASE IN COMPLEX WITH 3-((R)-1-(5-FLUORO-2-(2H-1,2,3- TRIAZOL-2-YL)PHENYL)ETHOXY)-5-(5-METHYL-1H-PYRAZOL- 4-YL)PYRIDIN-2-AMINE

STRUCTURE OF THE HUMAN ANAPLASTIC LYMPHOMA KINASE IN COMPLEX WITH 2-(5-(6-AMINO-5-((R)-1-(5-FLUORO-2 -(2H-1,2,3-TRIAZOL-2-YL)PHENYL)ETHOXY)PYRIDIN-3- YL)-4-METHYLTHIAZOL-2-YL)PROPAN-2-OL

ALK TYROSINE KINASE RECEPTOR (E.C.2.7.10.1)
Structure of L1196M Mutant Human Anaplastic Lymphoma Kinase in Complex with 2-(5-(6-amino-5-((R)-1-(5-fluoro-2-(2H-1,2,3-triazol-2- yl)phenyl)ethoxy)pyridin-3-yl)-4-methylthiazol-2-yl)propane-1,2-diol

The largest off-origin peak in the Patterson function is 6.67% of the height of the origin peak. No significant pseudotranslation is detected.

20191225.v01 (using entries in the PDB archive December 25th 2019)

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures