wwPDB validation report of PDB entry 8BI0

ABCG2 was incubated with 5mM ATP, 5mM MgCl2, 0.5mM ADP, 20 uM Tariquidar at room temperature for 10 min
ABCG2 in complex with Tariquidar under turnover condition

Broad substrate specificity ATP-binding cassette transporter ABCG2

ATP-binding cassette sub-family G member 2,Breast cancer resistance protein,CDw338,Mitoxantrone resistance-associated protein,Placenta-specific ATP-binding cassette transporter,Urate exporter

8BHT contains the same protein complexed with tariquidar but in the different conformation

ABCG2 turnover-2 state with tariquidar bound

(chain "B" and (resid 34 through 654 or resid 1501 through 1802))

(chain "A" and (resid 34 through 654 or resid 1501 through 1802))

Calculated fsc threesigma indicator curve
geometric validation package for ligand chemistry in protein x-ray structures
20191225.v01 (using entries in the PDB archive December 25th 2019)