wwPDB validation report of PDB entry 4B1T

BETA-TRYPSIN, ALPHA-TRYPSIN CHAIN 1, ALPHA-TRYPSIN CHAIN 2

BOVINE TRYPSIN COMPLEXED TO META-CYANO-BENZYLIC INHIBITOR

BOVINE TRYPSIN COMPLEXED TO BIS-PHENYLAMIDINE INHIBITOR

RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OF SERINE PROTEASES

RECRUITING ZINC TO MEDIATE POTENT, SPECIFIC INHIBITION OFSERINE PROTEASES

STRUCTURAL BASIS FOR SELECTIVITY OF A SMALL MOLECULE, S1-BINDING, SUB- MICROMOLAR INHIBITOR OF UROKINASE TYPE PLASMINOGEN ACTIVATOR

COMPLEX OF BDELLASTASIN WITH BOVINE TRYPSIN

BOVINE PANCREAS BETA-TRYPSIN IN COMPLEX WITH BENZAMIDINE

SUBTILISIN CARLSBERG (COMMERCIAL PRODUCT FROM SERRA, HEIDELBERG CALLED SUBTILISIN NAGARSE) COMPLEX WITH EGLIN- C

BOVINE TRYPSIN COMPLEXED WITH 2-[3-AMINO(IMINOMETHYL) PHENOXY]-6-[3-(AMINOMETHYL)PHENOXY]-3,5-DIFLUORO-4- METHYLPYRIDINE (ZK-806299), BINDING MODEL FROM DOUBLE REDOR NMR AND MD SIMULATIONS

BOVINE TRYPSIN COMPLEXED WITH 2,6-BIS[3-AMINO(IMINO )METHYL PHENOXY]-3,5-DIFLUORO-4-METHYLPYRIDINE (ZK- 805623), BINDING MODEL FROM DOUBLE REDOR NMR AND MD SIMULATIONS

CRYSTAL STRUCTURE OF CANCER CHEMOPREVENTIVE BOWMAN-BIRK INHIBITOR IN TERNARY COMPLEX WITH BOVINE TRYPSIN AT 2 .3 A RESOLUTION. STRUCTURAL BASIS OF JANUS-FACED SERINE PROTEASE INHIBITOR SPECIFICITY

PROTEINASE INHIBITOR EGLIN C WITH HYDROLYSED REACTIVE 1EGP 3CENTER 1EGP 4

CRYSTAL STRUCTURE OF THE BPTI ALA16LEU MUTANT IN COMPLEX WITH BOVINE TRYPSIN

CRYSTAL STRUCTURE OF A SERPIN:PROTEASE COMPLEX

CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN BOVINE BETA- TRYPSIN AND MCTI-A, A TRYPSIN INHIBITOR OF SQUASH FAMILY AT 1.8 A RESOLUTION

BOVINE BETA-TRYPSIN BOUND TO META-AMIDINO SCHIFF BASEMAGNESIUM(II) CHELATE

BOVINE BETA-TRYPSIN BOUND TO PARA-AMIDINO SCHIFF BASEIRON(III) CHELATE

BOVINE BETA-TRYPSIN BOUND TO META-AMIDINO SCHIFF BASECOPPER (II) CHELATE

BOVINE BETA-TRYPSIN BOUND TO PARA-AMIDINO SCHIFF- BASECOPPER (II) CHELATE

CRYSTAL STRUCTURE OF BETA-TRYSIN COMPLEX IN CYCLOHEXANE

BETA-TRYPSIN GUANIDINOBENZOYLATED AT SERINE 195 (PH 5. 5)

A NOVEL SERINE PROTEASE INHIBITION MOTIF INVOLVING A MULTI-CENTERED SHORT HYDROGEN BONDING NETWORK AT THE ACTIVE SITE

ENGINEERING INHIBITORS HIGHLY SELECTIVE FOR THE S1 SITES OFSER190 TRYPSIN-LIKE SERINE PROTEASE DRUG TARGETS

ATOMIC RESOLUTION STRUCTURES OF TRYPSIN PROVIDE INSIGHT INTO STRUCTURAL RADIATION DAMAGE

CRYSTAL STRUCTURE OF BENZAMIDINE INHIBITED BOVINEPANCREATIC TRYPSIN AT 105K TO 1.21A RESOLUTION FROMLABORATORY SOURCE WITH HIGH NUMBER OF WATERS MODELLED

CRYSTAL STRUCTURE OF TRYPSIN COMPLEX WITH AMYLAMINE INCYCLOHEXANE

HEMIACETAL COMPLEX BETWEEN LEUPEPTIN AND TRYPSIN

CRYSTAL STRUCTURE OF TRYPSIN IN COMPLEX WITH 79.

MESENTERICOPEPTIDASE PEPTIDYL PEPTIDE HYDROLASE COMPLEX WITH EGLIN-C

FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN

POTENT, SMALL MOLECULE INHIBITORS OF HUMAN MAST CELLTRYPTASE. ANTI-ASTHMATIC ACTION OF A DIPEPTIDE- BASEDTRANSITION STATE ANALOGUE CONTAINING BENZOTHIAZOLE KETONE

MODIFIED BETA TRYPSIN (MONOISOPROPYLPHOSPHORYL INHIBITED) ( NEUTRON DATA)

ELABORATE MANIFOLD OF SHORT HYDROGEN BOND ARRAYS MEDIATINGBINDING OF ACTIVE SITE-DIRECTED SERINE PROTEASE INHIBITORS

NON-COVALENT COMPLEX BETWEEN ALPHA-1-PI-PITTSBURGH ANDS195A TRYPSIN

CRYSTAL STRUCTURE OF THE BOVINE TRYPSIN COMPLEX WITH ASYNTHETIC 11 PEPTIDE INHIBITOR

STRUCTURAL CONSEQUENCES OF ACCOMMODATION OF FOUR NON- COGNATE AMINO-ACID RESIDUES IN THE S1 POCKET OF BOVINETRYPSIN AND CHYMOTRYPSIN

TRYPSIN COMPLEX WITH NONCOVALENTLY BOUND NAPAP

TRYPSIN COMPLEX WITH (CUCURBITA MAXIMA) TRYPSIN INHIBITOR (CMTI-I)

TRYPSIN COMPLEX WITH NONCOVALENTLY BOUND 3-TAPAP

BOVINE TRYPSIN 2-AMINOBENZIMIDAZOLE COMPLEX

BOVINE TRYPSIN WITH 1-[2-[5-[AMINO(IMINO)METHYL]-2 - HYDROXYPHENOXY]-6-[3-(4,5-DIHYDRO-1-METHYL-1H- IMIDAZOL-2-YL) PHENOXY]PYRIDIN-4-YL]PIPERIDINE-3- CARBOXYLIC ACID (ZK- 806974)

BOVINE TRYPSIN 3,3'-[3,5-DIFLUORO-4-METHYL-2, 6- PYRIDINEDIYLBIS(OXY)]BIS(BENZENECARBOXIMIDAMIDE) (ZK-805623 ) COMPLEX

BOVINE TRYPSIN 7-[[2-[[1-(1-IMINOETHYL)PIPERIDIN-4- YL]OXY]- 9H-CARBOZOL-9-YL] METHYL]NAPHTHALENE-2- CARBOXIMIDAMIDE (ZK- 806450) COMPLEX

BOVINE TRYPSIN 2-[AMINO(IMINO)METHYL]-2-HYDROXYPHENOXY ]-6- [3-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)PHENOXY] PYRIDINE-4- CARBOXYLIC ACID (ZK-806688) COMPLEX

BOVINE TRYPSIN 7-[[6-[[1-(1-IMINOETHYL)PIPERIDIN-4- YL]OXY]- 2-METHYL-BENZIMIDAZOL-1-YL]METHYL]NAPHTHALENE -2- CARBOXIMIDAMID ZK-806711 INHIBITOR COMPLEX

CRYSTAL STRUCTURE OF THE RWJ-51084 BOVINE PANCREATIC BETA- TRYPSIN AT 1.8 A

STRUCTURE OF TRYPSIN (ORTHORHOMBIC) WITH 1-(4-TERT- BUTYLCARBAMOYL- PIPERAZINE-1-CARBONYL)-3-(3-GUANIDINO- PROPYL)-4-OXO-AZETIDINE-2-CARBOXYLIC ACID

BOVINE PANCREATIC TRYPSIN INHIBITED WITH BENZAMIDINE ATATOMIC RESOLUTION

SUBTILISIN NOVO BPN' COMPLEX WITH EGLIN C MUTANT WITH LEU 45 REPLACED BY ARG (L45R)

CRYSTAL STRUCTURE OF MUNG BEAN INHIBITOR LYSINE ACTIVE FRAGMENT COMPLEX WITH BOVINE BETA-TRYPSIN AT 1.8A RESOLUTION

HIGH RESOLUTION STRUCTURE OF A POTENT, CYCLIC PROTEASE INHIBITOR FROM SUNFLOWER SEEDS

SUBTILISIN NOVO (BPN') COMPLEX WITH EGLIN C MUTANT WITH ARG 53 REPLACED BY LYS (R53K)

TRYPSIN COMPLEXED WITH BOWMAN-BIRK INHIBITOR

TRYPSIN COMPLEX WITH BOWMAN-BIRK INHIBITOR (AB-I)

TRYPSINOGEN COMPLEX WITH PORCINE PANCREATIC SECRETORY TRYPSIN INHIBITOR

TRYPSINOGEN (173 DEGREES K, 0.70 METHANOL, 0.30 WATER)

HIGH PACKING DENSITY FORM OF BOVINE BETA-TRYPSIN IN CYCLOHEXANE

TRYPSIN COMPLEXED WITH THE INHIBITOR AMINOMETHYLCYCLOHEXANE

TRYPSIN COMPLEXED WITH THE INHIBITOR 4-FLUOROBENZYLAMINE

TRYPSIN COMPLEXED WITH THE INHIBITOR 4-PHENYLBUTYLAMINE

TRYPSIN COMPLEXED WITH THE INHIBITOR 2-PHENYLETHYLAMINE

TRYPSIN COMPLEXED WITH THE INHIBITOR 3-PHENYLPROPYLAMINE

TRYPSIN COMPLEXED WITH THE INHIBITOR TRANYLCYPROMINE

ANHYDRO-TRYPSIN COMPLEX WITH PANCREATIC TRYPSIN INHIBITOR

BETA-TRYPSIN COMPLEX WITH P-AMIDINO-PHENYL-PYRUVATE ( APPA)

TRYPSIN COMPLEXED WITH INHIBITOR A90720A

BOVINE TRYPSIN COMPLEXED WITH P- AMIDINOPHENYLMETHYLPHOSPHINIC ACID (AMPA)

BETA TRYPSIN COMPLEXED WITH CYCLOTHEONAMIDE A

TRYPSIN SPECIFICITY AS ELUCIDATED BY LIE CALCULATIONS, X -RAY STRUCTURES AND ASSOCIATION CONSTANT MEASUREMENTS

BENZAMIDINE IN COMPLEX WITH BOVINE TRYPSIN VARIANT X( SSRI)BT.C1

FACTOR XA SPECIFIC INHIBITOR IN COMPLEX WITH BOVINE TRYPSINVARIANT X(TRIPLE.GLU)BT.D2

BENZAMIDINE IN COMPLEX WITH BOVINE TRYPSIN VARIANTX( TRIPLE.GLU)BT.D1

BENZAMIDINE IN COMPLEX WITH BOVINE TRYPSIN VARIANTX( TRIPLE.GLU)BT.A1

POTENT FACTOR XA INHIBITOR IN COMPLEX WITH BOVINE TRYPSINVARIANT X(99/175/190)BT

TRYPSIN INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN VARIANTX(SSYI)BT.B4

TRYPSIN INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN VARIANTX(SSYI)BT.A4

TRYPSIN INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN VARIANTX(SSWI)BT.B4

TRYPSIN INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN VARIANTX(SSRI)BT.B4

BENZAMIDINE IN COMPLEX WITH BOVINE TRYPSIN VARIANTX(SSFI .GLU)BT.D1

TRYPSIN INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN VARIANTX(SSFI.GLU)BT.B4

BENZAMIDINE IN COMPLEX WITH BOVINE TRYPSIN VARINAT X( SSAI)BT.D1

BENZAMIDINE IN COMPLEX WITH BOVINE TRYPSIN VARIANT X( SSAI)BT.C1

TRYPSIN INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN VARIANTX(SSAI)BT.B4

DIANHYDROSUGAR-BASED BENZAMIDINE, FACTOR XA SPECIFICINHIBITOR IN COMPLEX WITH BOVINE TRYPSIN MUTANT

TRYPSIN INHIBITORS WITH RIGID TRIPEPTIDYL ALDEHYDES

CRYSTAL STRUCTURE OF KUNITZ DOMAIN 1 OF TISSUE FACTORPATHWAY INHIBITOR-2 WITH BOVINE TRYPSIN

ON THE ROUTINE USE OF SOFT X-RAYS IN MACROMOLECULARCRYSTALLOGRAPHY, PART III- THE OPTIMAL DATA COLLECTIONWAVELENGTH

GUANIDINOBENZOYL-TRYPSIN ACYL-ENZYME AT 1.13 A RESOLUTION

CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN TRYPSIN ANDA DESIGNED SYNTHETIC HIGHLY POTENT INHIBITOR IN THEPRESENCE OF BENZAMIDINE AT 0.97 A RESOLUTION

BOVINE TRYPSIN IN COMPLEX WITH SQUASH SEED INHIBITOR ( CUCURBITA PEPO TRYPSIN INHIBITOR II)

IS RADIATION DAMAGE DEPENDENT ON THE DOSE-RATE USED DURING MACROMOLECULAR CRYSTALLOGRAPHY DATA COLLECTION

BOVINE PANCREAS BETA-TRYPSIN IN COMPLEX WITH BENZYLAMINE

CRYSTAL COMPLEX BETWEEN BOVINE TRYPSIN AND VERONICA HEDERIFOLIA TRYPSIN INHIBITOR

CRYSTAL STRUCTURE OF A BPTI VARIANT (CYS14->SER, CYS38 ->SER) IN COMPLEX WITH TRYPSIN

CRYSTAL STRUCTURE OF A BPTI VARIANT (CYS14->SER) IN COMPLEXWITH TRYPSIN

CRYSTAL STRUCTURE OF A BPTI VARIANT (CYS38->SER) IN COMPLEXWITH TRYPSIN

CRYSTAL STRUCTURE OF TRYPSIN COMPLEXED WITH BPTI AT 100K

CRYSTAL STRUCTURE OF TRYPSIN COMPLEXED WITH THE BPTIVARIANT (TYR35->GLY)

BOVINE TRYPSIN BOUND BY 4-PIPERIDINEBUTYRATE TO MAKEACYLENZYME COMPLEX

BOVINE TRYPSIN COMPLEXED WITH 2-AMINOBENZAMIDAZOLE

ROBOTICALLY HARVESTED TRYPSIN COMPLEXED WITH BENZAMIDINE CONTAINING POLYPEPTIDE MEDIATED CRYSTAL CONTACTS

BETA-TRYPSIN COMPLEX WITH PANCREATIC TRYPSIN INHIBITOR

TRYPSIN (ORTHORHOMBIC, 2.4 M AMMONIUM SULFATE)

SUBTILISIN CARLSBERG COMPLEX WITH GENETICALLY-ENGINEERED N -ACETYL EGLIN-C

THERMITASE COMPLEX WITH EGLIN-C (5 MILLIMOLAR CALCIUM)

TRYPSINOGEN, DIISOPROPYLPHOSPHORYL INHIBITED

TRYPSINOGEN COMPLEX WITH PANCREATIC TRYPSIN INHIBITOR

TRYPSINOGEN (103 DEGREES K, 0.70 METHANOL, 0.30 WATER)

LOW PACKING DENSITY FORM OF BOVINE BETA-TRYPSIN IN CYCLOHEXANE

BOVINE TRYPSIN COMPLEX WITH A MODIFIED SSI (STREPTOMYCES SUBTILISIN INHIBITOR) WITH MET 70 REPLACED BY GLY AND MET 73 REPLACED BY LYS (SSI(M70G,M73K))

TRYPSINOGEN - PANCREATIC TRYPSIN INHIBITOR - ILE-VAL COMPLEX (2.4 M MAGNESIUM SULFATE)

STRUCTURE OF A TICK TRYPTASE INHIBITOR IN COMPLEX WITH BOVINE TRYPSIN

BOVINE TRYPSIN IN COMPLEX WITH EVOLUTIONARY ENHANCED SCHISTOCERCA GREGARIA PROTEASE INHIBITOR 1 (SGPI-1-P02)

THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN THE BOVINE BETA-TRYPSIN AND TEN P1 VARIANTS OF BPTI.

THE CRYSTAL STRUCTURES OF THE COMPLEXES BETWEEN BOVINE BETA- TRYPSIN AND TEN P1 VARIANTS OF BPTI.

BETA-TRYPSIN (BENZAMIDINE INHIBITED) AT PH7

TRYPSIN (TRIGONAL, 2.4 M AMMONIUM SULFATE)

THERMITASE COMPLEX WITH EGLIN-C (100 MILLIMOLAR CALCIUM )

TRYPSINOGEN COMPLEX WITH PANCREATIC TRYPSIN INHIBITOR AND ILE-VAL

FRAGMENTS BOUND TO BOVINE TRYPSIN FOR THE SAMPL CHALLENGE

CO-COMPLEX STRUCTURE OF BOVINE TRYPSIN WITH A MODIFIED BOWMAN-BIRK INHIBITOR (PTA)SFTI-1(1,14), THAT WAS 1,4-DISUBSTITUTED WITH A 1,2,3-TRIZOL TO MIMIC A TRANS AMIDE BOND

CO-COMPLEX STRUCTURE OF BOVINE TRYPSIN WITH A MODIFIED BOWMAN-BIRK INHIBITOR (ICA)SFTI-1(1,14), THAT WAS 1,5-DISUBSTITUTED WITH 1,2,3-TRIZOL TO MIMIC A CIS AMIDE BOND

CATIONIC TRYPSIN IN COMPLEX WITH MUTATED SPINACIA OLERACEA TRYPSIN INHIBITOR III (SOTI-III) (F14A)

CATIONIC TRYPSIN IN COMPLEX WITH THE SPINACIA OLERACEA TRYPSIN INHIBITOR III (SOTI-III)

STRUCTURE OF THE FACTOR XA-LIKE TRYPSIN VARIANT TRIPLE -ALA (TGA) IN COMPLEX WITH EGLIN C

STRUCTURE OF THE FACTOR XA-LIKE TRYPSIN VARIANT TRIPLE -ALA (TGPA) IN COMPLEX WITH EGLIN C

STRUCTURE OF THE FACTOR XA-LIKE TRYPSIN VARIANT TRIPLE -ALA (TPA) IN COMPLEX WITH EGLIN C

TRYPSINOGEN COMPLEX WITH THE ARG==15==-ANALOGUE OF PANCREATIC TRYPSIN INHIBITOR AND VAL-VAL

STRUCTURE OF HYDROLASE (SERINE PROTEINASE)

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.

CATIONIC TRYPSIN (E.C.3.4.21.4), EGLIN C
Structure of the factor Xa-like trypsin variant triple-Ala (TA) in complex with eglin C

The largest off-origin peak in the Patterson function is 5.28% of the height of the origin peak. No significant pseudotranslation is detected.

20191225.v01 (using entries in the PDB archive December 25th 2019)

structure factor analysis and validation

geometric validation package for ligand chemistry in protein x-ray structures