The binary complex of D-3-hydroxybutyrate dehydrogenase with NAD+

Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor.

16%(w/v) PEG 8000, 100mM magnesium chloride, 100mM HEPES-Na buffer, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 293K

The same enzyme with the open conformation

The same enzyme with the closed conformation

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

D(-)-3-hydroxybutyrate dehydrogenase (E.C.1.1.1.30)

short chain dehydrogenase/reductase, SDR family, NAD, NADH, HBDH, OXIDOREDUCTASE