The structure of Trehalose Synthase (TreS) of Mycobacterium smegmatis

The Structure of the Mycobacterium Smegmatis Trehalose Synthase Reveals an Unusual Active Site Configuration and Acarbose-Binding Mode.

MALTOSE ALPHA-D-GLUCOSYLTRANSFERASE, MTASE

0.1 M SODIUM CACODYLATE BUFFER PH 6.5, 0.2 M MGCL2, 10% PEG 1000

NOVEL ACTIVE SITE AND INHIBITION SITES IDENTIFIED IN TREHALOSE SYNTHASE

SHEET
DETERMINATION METHOD: DSSP
THE SHEETS PRESENTED AS "AA" IN EACH CHAIN ON SHEET RECORDS
BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY
A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS
ARE IDENTICAL.

THE SHEETS PRESENTED AS "BA" IN EACH CHAIN ON SHEET RECORDS
BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY
A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS
ARE IDENTICAL.

TREHALOSE SYNTHASE/AMYLASE TRES (E.C.3.2.1.1, 5.4.99.16)

HYDROLASE, GLYCOHYDROLASE, DRUG DESIGN, TUBERCULOSIS