Crystal structure of the LecB lectin from Pseudomonas aeruginosa in complex with Methyl 6-(2,4,6-trimethylphenylsulfonylamido)-6-deoxy-alpha-D-mannopyranoside

Discovery of Two Classes of Potent Glycomimetic Inhibitors of Pseudomonas Aeruginosa Lecb with Distinct Binding Modes.

KIRKPATRICK-BAEZ PAIR OF BI-MORPH MIRRORS PLUS CHANNEL CUT CRYOGENICALLY COOLED MONOCHROMATOR CRYSTAL

330 MM SODIUM CACODYLATE PH 6.5 200 MM AMMONIUM SULPHATE 30% PEG8K

SHEET
DETERMINATION METHOD: AUTHOR PROVIDED.

THE N-TERMINAL METHIONINE IS MISSING FROM THE MATURE PROTEIN AND ALL THE NUMBERING HAS BEEN SHIFTED BY ONE

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. U VALUES REFINED INDIVIDUALLY. DISORDERED SIDE CHAIN WERE MODELED STEREOCHEMICALLY

SUGAR BINDING PROTEIN, GLYCOMIMETIC, INHIBITOR