Molecular basis for the enzymatic macrocyclization of multiply backbone N-methylated peptides

0.2 M sodium acetate, 0.1 M Bis-Tris propane (pH 6.0-6.5) and 28% PEG 3350

Biotechnology and Biological Sciences Research Council (BBSRC)

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : WITH TLS ADDED

macrocyclase for omphalotin A biosynthesis, HYDROLASE