The crystal structure of the nucleosome containing a cancer-associated histone H2A.Z R80C mutant

Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.

Rotated-inclined double-crystal monochromator, Si(111)

Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l

HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ

HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4

potassium cacodylate, potassium chloride, manganese chloride

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development
Platform Project for Supporting Drug Discovery and Life Science Research

Histone H3.1, Histone H4, Histone H2A.Z, Histone H2B type 1-J/DNA Complex

DNA binding, nucleus, chromatin formation, histone fold, histone, nucleosome, chromatin, DNA BINDING PROTEIN-DNA complex