HtrA1 inactive protease domain S328A with CARASIL mutations D174R R274Q

Repair strategies addressing pathogenic protein conformations

High-temperature requirement A serine peptidase 1,L56,Serine protease 11

1.6 M ammonium sulfate, 100 mM Citrate pH 4

6Z0E contains the same protein just with the mutations R274Q S328A

6Z0X contains the same protein with lower resolution and not twinned

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY

Hydrolase Protease HtrA family CARASIL mutations trimerization, HYDROLASE