The crystal structure of human Atg4B- LC3(1-120) complex

The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy.

Microtubule-associated proteins 1A/1B light chain 3B

HsAtg4B, Autophagy-related protein 4 homolog B, hAPG4B, Autophagin-1, Autophagy-related cysteine endopeptidase 1, AUT-like 1 cysteine endopeptidase

LC3, Microtubule-associated protein 1 light chain 3 beta, MAP1A/MAP1B LC3 B, MAP1A/1B light chain 3 B, MAP1 light chain 3-like protein 2, Autophagy-related protein LC3 B, Autophagy-related ubiquitin-like modifier LC3 B

20% PEG 3350, 0.1M sodium citrate, pH 5.8, VAPOR DIFFUSION, SITTING DROP, temperature 293K

The biological assembly is a hetero-dimer of molecules A and B.

papain-like fold, ubiquitin fold, HYDROLASE-STRUCTURAL PROTEIN COMPLEX