Molecular snapshots of drug release from tubulin: 1 millisecond after photoactivation.

Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography.

Release of a photopharmacological drug from its protein target captured by time-resolved serial crystallography

Designed Ankyrin Repeat Protein (DARPIN) D1

Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain

0.2M Ammonium sulfate, 0.1M Bis/Tris-methane pH=5.5, 21% PEG 3000 (m/v)

time-resolved serial crystallography, tubulin dynamics, azobenzene dynamics, CELL CYCLE