Crystal structure of Aldehyde dehydrogenase 1A1 from mouse

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

3-deoxyglucosone dehydrogenase,ALDH-E1,ALHDII,Aldehyde dehydrogenase family 1 member A1,Aldehyde dehydrogenase,cytosolic,Retinal dehydrogenase 1,RALDH 1,RalDH1

0.2 M potassium iodide (pH 7.0) and 20% (w/v) polyethylene glycol 3,350

replace the unplausible assembly of chain F

National Natural Science Foundation of China (NSFC)

(chain A and (resid 10 through 16 or (resid 17 and (name N or name CA or name C or name O or name CB )) or resid 18 through 21 or (resid 22 and (name N or name CA or name C or name O or name CB )) or resid 23 through 35 or (resid 36 through 37 and (name N or name CA or name C or name O or name CB )) or resid 38 through 56 or (resid 57 through 58 and (name N or name CA or name C or name O or name CB )) or resid 59 through 68 or (resid 69 through 70 and (name N or name CA or name C or name O or name CB )) or resid 71 through 90 or (resid 91 and (name N or name CA or name C or name O or name CB )) or resid 92 through 100 or (resid 101 and (name N or name CA or name C or name O or name CB )) or resid 102 through 112 or (resid 113 and (name N or name CA or name C or name O or name CB )) or resid 114 through 130 or (resid 131 and (name N or name CA or name C or name O or name CB )) or resid 132 through 209 or (resid 210 and (name N or name CA or name C or name O or name CB )) or resid 211 through 248 or (resid 249 and (name N or name CA or name C or name O or name CB )) or resid 250 through 259 or (resid 260 and (name N or name CA or name C or name O or name CB )) or resid 261 through 264 or (resid 265 and (name N or name CA or name C or name O or name CB )) or resid 266 through 272 or (resid 273 and (name N or name CA or name C or name O or name CB )) or resid 274 through 307 or (resid 308 and (name N or name CA or name C or name O or name CB )) or resid 309 through 312 or (resid 313 and (name N or name CA or name C or name O or name CB )) or resid 314 through 327 or (resid 328 and (name N or name CA or name C or name O or name CB )) or resid 329 through 347 or (resid 348 and (name N or name CA or name C or name O or name CB )) or resid 349 through 352 or (resid 353 and (name N or name CA or name C or name O or name CB )) or resid 354 through 362 or (resid 363 and (name N or name CA or name C or name O or name CB )) or resid 364 through 366 or (resid 367 through 368 and (name N or name CA or name C or name O or name CB )) or resid 369 through 392 or (resid 393 and (name N or name CA or name C or name O or name CB )) or resid 394 through 397 or (resid 398 and (name N or name CA or name C or name O or name CB )) or resid 399 through 411 or (resid 412 and (name N or name CA or name C or name O or name CB )) or resid 413 through 434 or (resid 435 and (name N or name CA or name C or name O or name CB )) or resid 436 through 475 or (resid 476 through 477 and (name N or name CA or name C or name O or name CB )) or resid 478 through 501))
(chain B and (resid 10 through 14 or (resid 15 and (name N or name CA or name C or name O or name CB )) or resid 16 through 21 or (resid 22 and (name N or name CA or name C or name O or name CB )) or resid 23 through 35 or (resid 36 through 37 and (name N or name CA or name C or name O or name CB )) or resid 38 through 56 or (resid 57 through 58 and (name N or name CA or name C or name O or name CB )) or resid 59 through 68 or (resid 69 through 70 and (name N or name CA or name C or name O or name CB )) or resid 71 through 90 or (resid 91 and (name N or name CA or name C or name O or name CB )) or resid 92 through 100 or (resid 101 and (name N or name CA or name C or name O or name CB )) or resid 102 through 112 or (resid 113 and (name N or name CA or name C or name O or name CB )) or resid 114 through 130 or (resid 131 and (name N or name CA or name C or name O or name CB )) or resid 132 through 209 or (resid 210 and (name N or name CA or name C or name O or name CB )) or resid 211 through 248 or (resid 249 and (name N or name CA or name C or name O or name CB )) or resid 250 through 264 or (resid 265 and (name N or name CA or name C or name O or name CB )) or resid 266 through 272 or (resid 273 and (name N or name CA or name C or name O or name CB )) or resid 274 through 307 or (resid 308 and (name N or name CA or name C or name O or name CB )) or resid 309 through 320 or (resid 321 and (name N or name CA or name C or name O or name CB )) or resid 322 through 347 or (resid 348 and (name N or name CA or name C or name O or name CB )) or resid 349 through 352 or (resid 353 and (name N or name CA or name C or name O or name CB )) or resid 354 through 362 or (resid 363 and (name N or name CA or name C or name O or name CB )) or resid 364 through 367 or (resid 368 and (name N or name CA or name C or name O or name CB )) or resid 369 through 377 or (resid 378 and (name N or name CA or name C or name O or name CB )) or resid 379 through 392 or (resid 393 and (name N or name CA or name C or name O or name CB )) or resid 394 through 397 or (resid 398 and (name N or name CA or name C or name O or name CB )) or resid 399 through 409 or (resid 410 and (name N or name CA or name C or name O or name CB )) or resid 411 through 434 or (resid 435 and (name N or name CA or name C or name O or name CB )) or resid 436 through 476 or (resid 477 and (name N or name CA or name C or name O or name CB )) or resid 478 through 501))
(chain C and (resid 10 through 14 or (resid 15 and (name N or name CA or name C or name O or name CB )) or resid 16 through 21 or (resid 22 and (name N or name CA or name C or name O or name CB )) or resid 23 through 35 or (resid 36 through 37 and (name N or name CA or name C or name O or name CB )) or resid 38 through 90 or (resid 91 and (name N or name CA or name C or name O or name CB )) or resid 92 through 100 or (resid 101 and (name N or name CA or name C or name O or name CB )) or resid 102 through 112 or (resid 113 and (name N or name CA or name C or name O or name CB )) or resid 114 through 130 or (resid 131 and (name N or name CA or name C or name O or name CB )) or resid 132 through 248 or (resid 249 and (name N or name CA or name C or name O or name CB )) or resid 250 through 259 or (resid 260 and (name N or name CA or name C or name O or name CB )) or resid 261 through 264 or (resid 265 and (name N or name CA or name C or name O or name CB )) or resid 266 through 272 or (resid 273 and (name N or name CA or name C or name O or name CB )) or resid 274 through 307 or (resid 308 and (name N or name CA or name C or name O or name CB )) or resid 309 through 312 or (resid 313 and (name N or name CA or name C or name O or name CB )) or resid 314 through 320 or (resid 321 and (name N or name CA or name C or name O or name CB )) or resid 322 through 324 or (resid 325 and (name N or name CA or name C or name O or name CB )) or resid 326 through 327 or (resid 328 and (name N or name CA or name C or name O or name CB )) or resid 329 through 347 or (resid 348 and (name N or name CA or name C or name O or name CB )) or resid 349 through 352 or (resid 353 and (name N or name CA or name C or name O or name CB )) or resid 354 through 366 or (resid 367 through 368 and (name N or name CA or name C or name O or name CB )) or resid 369 through 377 or (resid 378 and (name N or name CA or name C or name O or name CB )) or resid 379 through 392 or (resid 393 and (name N or name CA or name C or name O or name CB )) or resid 394 through 409 or (resid 410 and (name N or name CA or name C or name O or name CB )) or resid 411 or (resid 412 and (name N or name CA or name C or name O or name CB )) or resid 413 through 434 or (resid 435 and (name N or name CA or name C or name O or name CB )) or resid 436 through 475 or (resid 476 through 477 and (name N or name CA or name C or name O or name CB )) or resid 478 through 501))
(chain D and (resid 10 through 14 or (resid 15 and (name N or name CA or name C or name O or name CB )) or resid 16 through 21 or (resid 22 and (name N or name CA or name C or name O or name CB )) or resid 23 through 35 or (resid 36 through 37 and (name N or name CA or name C or name O or name CB )) or resid 38 through 56 or (resid 57 through 58 and (name N or name CA or name C or name O or name CB )) or resid 59 through 68 or (resid 69 through 70 and (name N or name CA or name C or name O or name CB )) or resid 71 through 90 or (resid 91 and (name N or name CA or name C or name O or name CB )) or resid 92 through 100 or (resid 101 and (name N or name CA or name C or name O or name CB )) or resid 102 through 130 or (resid 131 and (name N or name CA or name C or name O or name CB )) or resid 132 through 209 or (resid 210 and (name N or name CA or name C or name O or name CB )) or resid 211 through 248 or (resid 249 and (name N or name CA or name C or name O or name CB )) or resid 250 through 259 or (resid 260 and (name N or name CA or name C or name O or name CB )) or resid 261 through 264 or (resid 265 and (name N or name CA or name C or name O or name CB )) or resid 266 through 272 or (resid 273 and (name N or name CA or name C or name O or name CB )) or resid 274 through 307 or (resid 308 and (name N or name CA or name C or name O or name CB )) or resid 309 through 320 or (resid 321 and (name N or name CA or name C or name O or name CB )) or resid 322 through 324 or (resid 325 and (name N or name CA or name C or name O or name CB )) or resid 326 through 327 or (resid 328 and (name N or name CA or name C or name O or name CB )) or resid 329 through 352 or (resid 353 and (name N or name CA or name C or name O or name CB )) or resid 354 through 362 or (resid 363 and (name N or name CA or name C or name O or name CB )) or resid 364 through 392 or (resid 393 and (name N or name CA or name C or name O or name CB )) or resid 394 through 411 or (resid 412 and (name N or name CA or name C or name O or name CB )) or resid 413 through 434 or (resid 435 and (name N or name CA or name C or name O or name CB )) or resid 436 through 475 or (resid 476 through 477 and (name N or name CA or name C or name O or name CB )) or resid 478 through 501))
(chain E and (resid 10 through 14 or (resid 15 and (name N or name CA or name C or name O or name CB )) or resid 16 or (resid 17 and (name N or name CA or name C or name O or name CB )) or resid 18 through 21 or (resid 22 and (name N or name CA or name C or name O or name CB )) or resid 23 through 35 or (resid 36 through 37 and (name N or name CA or name C or name O or name CB )) or resid 38 through 56 or (resid 57 through 58 and (name N or name CA or name C or name O or name CB )) or resid 59 through 68 or (resid 69 through 70 and (name N or name CA or name C or name O or name CB )) or resid 71 through 90 or (resid 91 and (name N or name CA or name C or name O or name CB )) or resid 92 through 100 or (resid 101 and (name N or name CA or name C or name O or name CB )) or resid 102 through 112 or (resid 113 and (name N or name CA or name C or name O or name CB )) or resid 114 through 130 or (resid 131 and (name N or name CA or name C or name O or name CB )) or resid 132 through 209 or (resid 210 and (name N or name CA or name C or name O or name CB )) or resid 211 through 248 or (resid 249 and (name N or name CA or name C or name O or name CB )) or resid 250 through 264 or (resid 265 and (name N or name CA or name C or name O or name CB )) or resid 266 through 272 or (resid 273 and (name N or name CA or name C or name O or name CB )) or resid 274 through 312 or (resid 313 and (name N or name CA or name C or name O or name CB )) or resid 314 through 320 or (resid 321 and (name N or name CA or name C or name O or name CB )) or resid 322 through 324 or (resid 325 and (name N or name CA or name C or name O or name CB )) or resid 326 through 347 or (resid 348 and (name N or name CA or name C or name O or name CB )) or resid 349 through 362 or (resid 363 and (name N or name CA or name C or name O or name CB )) or resid 364 through 366 or (resid 367 through 368 and (name N or name CA or name C or name O or name CB )) or resid 369 through 377 or (resid 378 and (name N or name CA or name C or name O or name CB )) or resid 379 through 397 or (resid 398 and (name N or name CA or name C or name O or name CB )) or resid 399 through 409 or (resid 410 and (name N or name CA or name C or name O or name CB )) or resid 411 through 434 or (resid 435 and (name N or name CA or name C or name O or name CB )) or resid 436 through 476 or (resid 477 and (name N or name CA or name C or name O or name CB )) or resid 478 through 501))
(chain F and (resid 10 through 14 or (resid 15 and (name N or name CA or name C or name O or name CB )) or resid 16 through 35 or (resid 36 through 37 and (name N or name CA or name C or name O or name CB )) or resid 38 through 56 or (resid 57 through 58 and (name N or name CA or name C or name O or name CB )) or resid 59 through 68 or (resid 69 through 70 and (name N or name CA or name C or name O or name CB )) or resid 71 through 90 or (resid 91 and (name N or name CA or name C or name O or name CB )) or resid 92 through 100 or (resid 101 and (name N or name CA or name C or name O or name CB )) or resid 102 through 112 or (resid 113 and (name N or name CA or name C or name O or name CB )) or resid 114 through 209 or (resid 210 and (name N or name CA or name C or name O or name CB )) or resid 211 through 248 or (resid 249 and (name N or name CA or name C or name O or name CB )) or resid 250 through 259 or (resid 260 and (name N or name CA or name C or name O or name CB )) or resid 261 through 264 or (resid 265 and (name N or name CA or name C or name O or name CB )) or resid 266 through 272 or (resid 273 and (name N or name CA or name C or name O or name CB )) or resid 274 through 307 or (resid 308 and (name N or name CA or name C or name O or name CB )) or resid 309 through 312 or (resid 313 and (name N or name CA or name C or name O or name CB )) or resid 314 through 324 or (resid 325 and (name N or name CA or name C or name O or name CB )) or resid 326 through 327 or (resid 328 and (name N or name CA or name C or name O or name CB )) or resid 329 through 347 or (resid 348 and (name N or name CA or name C or name O or name CB )) or resid 349 through 352 or (resid 353 and (name N or name CA or name C or name O or name CB )) or resid 354 through 362 or (resid 363 and (name N or name CA or name C or name O or name CB )) or resid 364 through 366 or (resid 367 through 368 and (name N or name CA or name C or name O or name CB )) or resid 369 through 377 or (resid 378 and (name N or name CA or name C or name O or name CB )) or resid 379 through 397 or (resid 398 and (name N or name CA or name C or name O or name CB )) or resid 399 through 434 or (resid 435 and (name N or name CA or name C or name O or name CB )) or resid 436 through 475 or (resid 476 through 477 and (name N or name CA or name C or name O or name CB )) or resid 478 through 501))
(chain G and (resid 10 through 14 or (resid 15 and (name N or name CA or name C or name O or name CB )) or resid 16 through 56 or (resid 57 through 58 and (name N or name CA or name C or name O or name CB )) or resid 59 through 68 or (resid 69 through 70 and (name N or name CA or name C or name O or name CB )) or resid 71 through 130 or (resid 131 and (name N or name CA or name C or name O or name CB )) or resid 132 through 259 or (resid 260 and (name N or name CA or name C or name O or name CB )) or resid 261 through 264 or (resid 265 and (name N or name CA or name C or name O or name CB )) or resid 266 through 307 or (resid 308 and (name N or name CA or name C or name O or name CB )) or resid 309 through 312 or (resid 313 and (name N or name CA or name C or name O or name CB )) or resid 314 through 324 or (resid 325 and (name N or name CA or name C or name O or name CB )) or resid 326 through 347 or (resid 348 and (name N or name CA or name C or name O or name CB )) or resid 349 through 352 or (resid 353 and (name N or name CA or name C or name O or name CB )) or resid 354 through 367 or (resid 368 and (name N or name CA or name C or name O or name CB )) or resid 369 through 377 or (resid 378 and (name N or name CA or name C or name O or name CB )) or resid 379 through 392 or (resid 393 and (name N or name CA or name C or name O or name CB )) or resid 394 through 397 or (resid 398 and (name N or name CA or name C or name O or name CB )) or resid 399 through 409 or (resid 410 and (name N or name CA or name C or name O or name CB )) or resid 411 or (resid 412 and (name N or name CA or name C or name O or name CB )) or resid 413 through 501))
(chain H and (resid 10 through 14 or (resid 15 and (name N or name CA or name C or name O or name CB )) or resid 16 or (resid 17 and (name N or name CA or name C or name O or name CB )) or resid 18 through 21 or (resid 22 and (name N or name CA or name C or name O or name CB )) or resid 23 through 35 or (resid 36 through 37 and (name N or name CA or name C or name O or name CB )) or resid 38 through 56 or (resid 57 through 58 and (name N or name CA or name C or name O or name CB )) or resid 59 through 68 or (resid 69 through 70 and (name N or name CA or name C or name O or name CB )) or resid 71 through 90 or (resid 91 and (name N or name CA or name C or name O or name CB )) or resid 92 through 100 or (resid 101 and (name N or name CA or name C or name O or name CB )) or resid 102 through 112 or (resid 113 and (name N or name CA or name C or name O or name CB )) or resid 114 through 130 or (resid 131 and (name N or name CA or name C or name O or name CB )) or resid 132 through 209 or (resid 210 and (name N or name CA or name C or name O or name CB )) or resid 211 through 248 or (resid 249 and (name N or name CA or name C or name O or name CB )) or resid 250 through 259 or (resid 260 and (name N or name CA or name C or name O or name CB )) or resid 261 through 272 or (resid 273 and (name N or name CA or name C or name O or name CB )) or resid 274 through 307 or (resid 308 and (name N or name CA or name C or name O or name CB )) or resid 309 through 312 or (resid 313 and (name N or name CA or name C or name O or name CB )) or resid 314 through 320 or (resid 321 and (name N or name CA or name C or name O or name CB )) or resid 322 through 324 or (resid 325 and (name N or name CA or name C or name O or name CB )) or resid 326 through 327 or (resid 328 and (name N or name CA or name C or name O or name CB )) or resid 329 through 347 or (resid 348 and (name N or name CA or name C or name O or name CB )) or resid 349 through 352 or (resid 353 and (name N or name CA or name C or name O or name CB )) or resid 354 through 362 or (resid 363 and (name N or name CA or name C or name O or name CB )) or resid 364 through 366 or (resid 367 through 368 and (name N or name CA or name C or name O or name CB )) or resid 369 through 392 or (resid 393 and (name N or name CA or name C or name O or name CB )) or resid 394 through 397 or (resid 398 and (name N or name CA or name C or name O or name CB )) or resid 399 through 409 or (resid 410 and (name N or name CA or name C or name O or name CB )) or resid 411 or (resid 412 and (name N or name CA or name C or name O or name CB )) or resid 413 through 434 or (resid 435 and (name N or name CA or name C or name O or name CB )) or resid 436 through 475 or (resid 476 through 477 and (name N or name CA or name C or name O or name CB )) or resid 478 through 501))