Cholest-4-en-3-one bound structure of CYP142 from Mycobacterium smegmatis

A Highly Conserved Mycobacterial Cholesterol Catabolic Pathway.

LIGAND-FREE STRUCTURE OF CYP142 FROM MYCOBACTERIUM SMEGMATIS

PROTOPORPHYRIN IX CONTAINING FE (HEM): THIOLATE BOND TO CYS
343
(8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE (K2B): SUBSTRATE
MAGNESIUM ION (MG): PART OF CRYSTALLIZATION CONDITIONS

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS.