Crystal structure of TNIK-AMPPNP-thiopeptide TP15 complex

PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER

(2Z)-2-amino-3-sulfanylprop-2-enoic acid

De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors.

TRAF2 and NCK-interacting protein kinase

ammonium acetate, MgSO4, Hepes-Na, PEG smear medium

ripp, thiopeptide, kinase inhibition, complex, SIGNALING PROTEIN, SIGNALING PROTEIN-INHIBITOR complex