Crystal structure of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP

Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor.

ATP pyrophosphate-lyase, Adenylyl cyclase, Edema factor, EF, Anthrax edema toxin adenylate cyclase component

PEG400, magnesium chloride, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 278K

Calmodulin-sensitive adenylate cyclase (E.C.4.6.1.1), Calmodulin 2
protein-protein interactions, LYASE-METAL BINDING PROTEIN COMPLEX