Crystal structure of the phosphatidylinositol 4-kinase IIbeta

The high-resolution crystal structure of phosphatidylinositol 4-kinase II beta and the crystal structure of phosphatidylinositol 4-kinase II alpha containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design.

Phosphatidylinositol 4-kinase type 2-beta,Endolysin,Phosphatidylinositol 4-kinase type 2-beta
UNP residues 90-165,UNP residues 2-164,UNP residues 176-450,UNP residues 90-165,UNP residues 2-164,UNP residues 176-450,UNP residues 90-165,UNP residues 2-164,UNP residues 176-450

Phosphatidylinositol 4-kinase type II-beta,PI4KII-BETA,Lysis protein,Lysozyme,Muramidase,Phosphatidylinositol 4-kinase type II-beta,PI4KII-BETA

100 mM MES/Imidazole pH = 6.5, 10% w/v PEG 4000, 20% v/v glycerol, 20 mM 1,6-hexanediol, 20 mM 1-butanol, 20 mM 1,2-propanediol, 20 mM 2-propanol, 20 mM 1,4-butanediol, 20 mM 1,3-propanediol

FP7-PEOPLE-2012-CIG, project number 333916

Chimera protein of Phosphatidylinositol 4-kinase 2-beta and Lysozyme (E.C.2.7.1.67,3.2.1.17)

lipid kinase, phosphatidyl inositol, transferase, hydrolase