Crystal structure of a BRAF kinase domain monomer

Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation.

Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1

0.1 M Tris, 0.2 M trimethylamine-N-oxide, 20% (w/v) PEG-MME 2,000

3C4C contains the same protein complexed with the same ligand.

Serine/threonine-protein kinase B-raf (E.C.2.7.11.1)

Kinase, Monomer, Inhibitor, Complex, TRANSFERASE-TRANSFERASE Inhibitor complex